Winter 2022 Class Schedule
First Year Seminars
|BIOL_SCI 101-6-04||First Year Seminar - The Genetic Basis of Disease||John Mordacq||
|BIOL_SCI 116-6||First Year Seminar - Science Research Preparation||Luke Flores||TTh 4:30-5:50pm|
|BIOL_SCI 109-0||The Nature of Plants||Paul CaraDonna||
|BIOL_SCI 241-0||Biochemistry, Molecular and Cell Biology - 2 for ISP||Vinzenz Unger||M-F 9-9:50am|
|BIOL_SCI 203-0||Genetics & Evolution||Erik Andersen & Joseph Walsh||
Sec. 1: MWF 10-10:50am
Sec. 2: MWF 11-11:50am
|BIOL_SCI 233-0||Genetics and Molecular Processes Laboratory||Jennifer Brace & John Mordacq||See Caesar Listing|
300 Level courses
|BIOL_SCI 303-0||Molecular Neurobiology||Tracy Hodgson||
|BIOL_SCI 310-0||Human Physiology||Tracy Hodgon||
|BIOL_SCI 315-0||Advanced Cell Biology||Greg Beitel||
|BIOL_SCI 323-0||Bioinformatics||Ishwar Radhakrishnan||
|BIOL_SCI 338||Modeling Biological Dynamics||Rosemary Braun||
|BIOL_SCI 349-0||Community Ecology||Amy Iler||TTh 8:30-9:50am|
|BIOL_SCI 350-0||Plant Evolution & Diversity Laboratory||Patrick Herendeen||
|BIOL_SCI 355-0||Immunobiology||Hilary Truchan||
|BIOL_SCI 377-0||The Human Microbiome||Hilary Truchan||
|BIOL_SCI 378-0||Functional Genomics||Eric Weiss||
|BIOL_SCI 381-0||Stem Cells & Regeneration||Christian Petersen||
|BIOL_SCI 397-0||Honors Colloquium||Gary Galbreath|
Winter 2022 course descriptions
First Year Seminars & 100 Level courses
We will study the alterations to the genome that are responsible for various human diseases. Students will learn about traditional and potential experimental targeted treatment (gene-editing) of the diseases. We will discuss the impact of these diseases on healthcare as well as their social implications. Discussions will center on scientific studies and literature. The course is structured to increase the basic understanding of human genetics.
Registration Requirement: First-years only.
This course will provide students with skills and training to be successful in research environments. Under the guidance of faculty, graduate mentors and peer facilitators, students are expected to develop an independent research project, write a research funding proposal, give an oral presentation on their project, and develop basic laboratory skills.
Registration Requirements: enrollment open only to participants in the Bioscientist program. Students should contact Dr. Flores to obtain a permission number.
This courseis meant to be a gateway into the fascinating world of plants. It is designed to give students an exciting and stimulating understanding of the biology and ecology of all plants, while at the same time not overwhelming students with levels of detail and specialized terminology that are not useful to non-science-majors. We will learn how plants make food, move around to new places, reproduce, deal with extreme weather, and defend themselves against natural enemies. We will investigate the partnerships plants form with other groups of organisms, such as those with animal pollinators, fungi, and animal body guards. We will consider how plant form and function relates to global biodiversity patterns and contributes to the healthy functioning of ecosystems everywhere. Finally, throughout all of these topics, we will consider how humans use plants as sources of food, fiber, shelter, medicines, drugs, and more.
This course will present the fundamentals of genetics and evolution. From the rules of heredity to the complex genetics of humans, we will cover the methods and logic of genetics as applied to inheritance, development, neurobiology, and populations. These concepts will transition to the process and tempo of evolution. From natural selection to speciation, we will cover evolution with an emphasis on how genetics plays a critical role.
Prerequisite: Students must have completed, with a C- or better, BIOL_SCI 202-0 or 219-0 to register for this course. Must be taken concurrently with BIOL_SCI 233-0.
Natural Sciences Distro Area
This is the second course in a three-quarter sequence of introductory biology laboratory, which meets once a week for four hours and includes an online lecture component. The course is designed to provide students with an authentic laboratory experience that investigates relevant scientific research and teaches scientific inquiry skills such as experimental design, writing research proposals, data collection, data analysis/interpretation, and the presentation of results. The experimental model revolves around aggregate prone proteins in nematodes and how RNA interference (RNAi) can be used to affect protein folding and the clearance of protein aggregates. Students will learn and become proficient at various cell and molecular biology techniques.
Prerequisite: Students must have completed BIOL_SCI 232-0. Must be taken concurrently with BIOL_SCI 203-0. Credit not allowed for both BIOL_SCI 220-0 and BIOL_SCI 233-0.
Extending the biochemistry segment from Biol_Sci 240, this class seeks to provide deeperunderstanding of select topics in biochemistry, including the structure and function of macromolecules, biological transport and signaling, chemical logic of metabolic reactions and select cellular pathways. The course strongly emphasizes conceptual understanding and aims to develop and integrated understanding that allows students to apply their knowledge to solve complex problems. Pre-requistites: General Chemistry 171, 172 Organic Chemistry Chem 212-1 BiolSci 240 (Instructor Permission required if missing).
300 level courses
This course will be part lecture course and part seminar, and will explore how the fields of neurobiology and molecular biology have converged to answer questions about the function of the central nervous system, in health and disease, and ethical considerations in the use of molecular biology techniques. Topics may include: Crispr -Cas9 system and gene editing; transgenic animals; molecular techniques employed to understand and treat neurological diseases such as Parkinson's disease and schizophrenia. Pre-requisites: Biol Sci 302-0 Fundamentals of Neurobiology I is required.
Biol_Sci 310 explores the functions of the human body with an emphasis on homeostatic mechanisms, interdependence of organs and organ systems and the influence of modulatory systems. Topics include: nervous, cardiovascular, respiratory, renal, and digestive systems as well as endocrine application in these systems. Readings and activities focusing on the contributions of scientists of color to the advancement of physiology, and examples of social injustice that have occurred during the pursuit of physiology research, will be included.
Prerequisites: Students must have completed BIOL_SCI 201-0 or BIOL_SCI 215-0, BIOL_SCI 202-0 or BIOL_SCI 219-0, and CHEM 132-0, CHEM 152-0, or CHEM 172-0. Credit not allowed for both BIOL_SCI 310-0 and BIOL_SCI 217-0.
Current themes and experimental approaches in cell biology will be discussed through readings of text and original research articles.Discussion sections will focus on experimental approaches, includingcontrolsand statistical significance,and understanding data as presented in primary literature. Pre-requisites: BIO 215, 219; 301 or 308.
In a knowledge-based economy, critical thinking and coding skills are paramount for success. This course will prepare students to address informatics challenges in academia and industry. The course will explore through case studies and classroom discussions, the principles and practical applications of computational tools in contemporary molecular and structural biology research. Besides gaining an appreciation for the algorithmic aspects of these tools and their limitations, students will learn to code in Python, design and perform experiments in silico, and critically evaluate results. Pre-requisities: BIOL SCI 241, BIOL SCI 301, OR equivalent; BIOL SCI 361 OR equivalent recommended but not required. Aptitude for computers and software is required; coding experience would be advantageous but not required.
Life is an inherently dynamic process, and the dynamics at every scale of organization -- from the atomic self-assembly of macromolecular complexes to the interactions of species in an ecology -- can give rise to surprising outcomes. Predicting and modulating those dynamics requires the development of accurate mathematical and computational models. In this class, you will learn about mathematical and computational techniques for analyzing and predicting biological dynamics. Techniques will include statistical models, discrete- and continuous- time dynamical models, and stochastic models. Applications will cover a range of scales, from biomolecules to population dynamics, with an emphasis on common mathematical concepts and computational techniques, the interpretation of existing data, and making predictions for new experiments.
Prerequisites: at least one of MATH 218-1, MATH 220-1, MATH 240-0, STAT 202-0, BIOL_SCI 337-0, OR equivalent.
Community ecology investigates the dynamics, structure, and function of assemblages of organisms. Readings, discussions, lectures, and activities will address how communities are organized, how they interact with their biotic and abiotic environments, how they are studied, and how they are influenced by anthropogenic impacts.
Prerequisite: The former BIOL_SCI 330-0 or BIOL_SCI 339-0.
This course is an introduction to the diversity and evolutionary history of land plants for advanced undergraduates and graduate students. It will introduce principles of plant structure, classification, phylogeny, and paleontology in an evolutionary framework. Morphological, anatomical, molecular and fossil evidence for the evolutionary history and relationships of each group will be presented. Laboratories will focus on diversity and structural characteristics of each group and their fossils.
Prerequisite: The former BIOL_SCI 330-0 or BIOL_SCI 339-0.
Immunobiology is the study of the response of higher organisms to foreign substances and pathogens, such as bacteria and viruses. This course examines the cells and organs of the vertebrate immune system and how they function to protect us against microbial infection. We will also briefly examinedisorders of the immune system, including immune deficiency, hypersensitivity, and autoimmune diseases. Prerequisites: BIOL_SCI 201 or BIOL_SCI 215; BIOL_SCI 219; and BIOL_SCI 301.
The ability to sense external and internal signals and dynamically respond lies at the core of cellular homeostasis and is one of the most important properties of all forms of life. In this course, general molecular principles of signaling through which cells capture, process, store and send information are discussed. The emphasis of this course in on the design principles, components, and molecular mechanisms that are common to different signaling systems. Modern experimental techniques for studying cellular signaling as well as the implications of disruption of cell communication pathways in diseases will be described.
The Human Microbiome is an introductory course on the collection of microorganisms in and on the body and the fascinating role they playin our health. We will explore different communities of microorganisms in the human body -the gut, urogenital, oral, and skin microbiota and learn about how those communities contribute to or are altered in healthy and diseased states. Topics will include, but are not limited to, the contribution of these communities to digestion and gut health, mood, obesity, the immune system, fertility and pregnancy, and neurological disorders. This is a rapidly expanding field, and we will place a special emphasis on exploring these topics through review of primary research articles.
Prerequisites: BIOL_SCI 202-0 or BIOL_SCI 219-0, BIOL_SCI 203-0 or BIOL_SCI 215-0, and BIOL_SCI 301-0.
Natural Sciences Distro Area
The use of stem cells for growth, repair, and maintenance of tissue is widespread throughout the animal kingdom. In addition, species vary in their natural abilities of repair tissue in adulthood, from wound healing and scar formation to complete cell/tissue/organ regeneration after damage. What are the molecular processes that imbue stem cells with their unique abilities, how are these controlled by the organism, and how can they be harnessedtherapeutically? This course takes a comparative approach to explore this fascinating problem by critically examining classic and modern scientific literature about the developmental and molecular biology of regeneration and both embryonic and adult stem cells.
A student intending to write a Thesis in Biological Sciences must register for Senior Thesis Colloquium (BIOL SCI 397) during Winter Quarter of the Senior Year.I t is in the context of this class that Senior or Honors Theses are written. Do not also register for a 399 that quarter; for the Winter, BIOL SCI 397 replaces 399 with regard to both your research and its write-up. Pre-requisities: At least one BIOL SCI 398 or 399 registration must have preceded BIOL SCI 397. Do not register for a 398 or 399 during the same quarter as 397.
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